@article{oai:nitech.repo.nii.ac.jp:00004543,
 author = {Watanabe, Yoshihiko and Ono, Yojiro and Ueno, Yoshio and Toru, Takeshi},
 issue = {6},
 journal = {Journal of the Chemical Society. Perkin transactions 1 : organic and bio-organic chemistry.},
 month = {Jan},
 note = {Oxidation of 2-(1-hydroxy-1-methylethyl)-1,3-dithiane with the Sharpless reagent has been examined under various reaction conditions. Oxidation of 2-(1-hydroxy-1-methylethyl)-1,3-dithiane with Ti(OPri)4-diethyl L-(+)-tartrate-tert-butyl hydroperoxide (1:2:1.5) in CH2Cl2  in the presence of 4 A molecular sieves gives (1S,2S)-2-(1-hydroxy-1-methylethyl)-1,3-dithiane 1-oxide with high trans selectivity and with moderate enantioselectivity. The enantioselectivity depends upon the substituent at the 2-position of the 1,3-dithiane. Oxidation of 2-(1-methoxy-1-methylethyl)- and 2-(1-acetoxy-1-methylethyl)-1,3-dithiane gives (1S,2S)-2-(1-methoxy-1-methylethyl)- and (1R,2S)-2-(1-acetoxy-1-methylethyl)-1,3-dithiane 1-oxides, respectively in >99% ee., application/pdf},
 pages = {1087--1093},
 title = {Asymmetric  oxidation of 1,3-dithianes to 1,3-dithiane 1-oxides},
 volume = {1998},
 year = {1998}
}